Caspase-3 Inhibitor Drug Screening Kit (Fluorometric) Caspase-3 Inhibitor -北京博迈斯科技发展有限公司-biovision-「北京博迈斯科技发展有限公司
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产品分类:细胞生物学
产品小类:Caspase活性检测试剂盒
货号: K153-100
产品名称:Caspase-3 Inhibitor Drug Screening Kit (Fluorometric) Caspase-3 Inhibitor -北京博迈斯科技发展有限公司
英文名称:Caspase-3 Inhibitor Drug Screening Kit (Fluorometric)
品牌:biovision
规格:100 assays
价格:6375
说明:

biovision K153-100 Cell samples treated with Caspase inhibitor drugs ? Detection method- Fluorescence (Ex/Em 400/505) ? Species reactivity- Mammalian ? Kit size- 100 assays ? Applications- Effective means for screening caspase inhibitors using fluorometric methods. Caspase-3 Inhibitor Drug Screening Kit: Rapid & Convenient Fluorometric Assay to Screen Caspase-3 Inhibitors. Includes Caspase-3 Inhibitor. 100 Assays. Caspases have been shown to play a crucial role in apoptosis induced by various deleterious and physiologic stimuli. Inhibition of caspases can delay apoptosis, implicating a potential role in drug screening efforts. The Caspase-3 Inhibitor Drug Screening Kit provides an effective means for screening caspase inhibitors using fluorometric methods. The assay utilizes synthetic peptide substrate DEVD-AFC (AFC, 7-amino-4-trifluoromethyl coumarin). Active caspase-3 cleaves the synthetic substrate to release free AFC which can then be quantified by fluorometry. Compounds to be screened can directly be added to the reaction and the level of inhibition of caspase-3 activity can be determined by comparison of the fluorescence intensity in samples with and without the testing inhibitors.


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